Hot Topic Schedule

October 28, 2012
10:30am - 12:00 pm
Bethesda North Marriott Hotel & Conference Center
North Bethesda, MD

Presentations are posted online based upon presenter approval.

Program Schedule

10:30 am – 10:35 am Welcome & Introductions
Suzanne L. Topalian, MD - Johns Hopkins University School of Medicine
10:35 am – 11:00 am PD-1 Pathway Blockade In Cancer Therapy: Clinical Results And Future Development
Suzanne L. Topalian, MD - Johns Hopkins University School of Medicine
11:00 am – 11:15 am Overcoming Tumor-Induced Negative Regulatory Pathways in Murine Models of Rhabdomyosarcoma
Steven L. Highfill, PhD - National Cancer Institute
11:15 am – 11:30 am Ovarian Tumor-Infiltrating T Cells and Myeloid Cells Mediate Immune Suppression Through The PD-1/PD-L1 Pathway
Jaikumar Duraiswamy, PhD - University of Pennsylvania
11:30 am – 11:55 am Considerations In Targeting PD-1, PD-L1, and Other Immune Checkpoints: Immunoediting and Mechanistic Perspectives
Ira Mellman, PhD - Genentech, Inc.
11:55 am - 12:00 pm Closing Comments/Questions & Answers


  • Go to SITC’s YouTube channel to hear Annual Meeting Organizers talk about highlights of the meeting!
  • October 24, 2012
    SITC Early Career Scientists Professional Development Session
  • October 24-25, 2012
    SITC Workshop – Focus on the Target: The Tumor Microenvironment
  • October 25, 2012
    SITC Primer on Tumor Immunology and Cancer Immunotherapy™
  • October 26-28, 2012
    SITC 27th Annual Meeting
  • October 28, 2012
    SITC Hot Topic Symposium: PD-1/PD-L1: Right on Target

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