Enduring Materials
Access slide decks and video via the links in the schedule below.
= PDF of slides is available
= Presentation video is available
Program Schedule
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11:00 a.m. – 11:10 a.m. | Welcome and Introductions Daniel Chen, MD, PhD – Genentech |
Session I: New Agents in DevelopmentModerator: Adrian Bot, MD, PhD – Kite Pharma, Inc. |
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11:10 a.m. – 11:15 a.m. | Anti-Semaphorin4D VX15/2503 in Combination with Ipilimumab or Antibody to PD-1 or PD-L1 Elizabeth Evans, PhD - Vaccinex, Inc |
11:15 a.m. – 11:20 a.m. | IMO-2125, An Investigational Intratumoral Toll-Like Receptor 9 Agonist, Modulates the Tumor Microenvironment to Enhance Anti-Tumor Immunity Mark Cornfeld, MD, MPH – Idera Pharmaceuticals |
11:20 a.m. – 11:25 a.m. | Cobimetinib in Combination with Atezolizumab Edward Cha – Genentech |
11:25 a.m. - 11:30 a.m. | Combination Strategy for Varlilumab, An Agonist Anti-CD27 Monoclonal Antibody Thomas Davis, MD – Celldex Therapeutics, Inc. |
11:30 a.m.- 11:35 a.m. | Safety of the Natural Killer (NK) Cell-Targeted Anti-KIR Antibody, lirilumab (liri), in Combination with Nivolumab (nivo) or Ipilimumab (ipi) in Two Phase 1 Studies in Advanced Refractory Solid Tumors F. Stephen Hodi, MD – Dana-Farber Cancer Institute |
11:35 a.m. - 11:40 a.m. | A CD122-Biased Agonist Increases CD8+T Cells and Natural Killer Cells in the Tumor Microenvironment; Making Cold Tumors Hot with NKTR-214 Adi Diab, MD – MD Anderson Cancer Center |
11:40 a.m. – 11:45 a.m. | Activated Natural Killer (aNK) Cell Therapy Patrick Soon-Shiong, MD, FRCS, FACS – NantKwest |
Session II: Pre-Clinical New Agents in Development
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11:45 a.m. – 11:50 a.m. | CD3-EGFR Probody™ T Cell-Engaging Bispecific Induces Tumor Regressions and Substantially Increases Safety Window in Preclinical Studies Bryan A. Irving, PhD – Cytomx Therapeutics, Inc. |
11:50 a.m. – 11:55 a.m. | PRS-343, a CD137 (4-1BB)/HER2 Bispecific Shane A. Olwill, PhD – Pieris Pharmaceuticals, Inc. |
11:55 a.m. – 12:00 p.m. | pLADD: Personalized, Live, Attenuated Double-Deleted Listeria Monocytogenes Thomas W. Dubensky Jr., PhD – Aduro Biotech |
12:00 p.m. – 12:05 p.m. | CA170: A Small Molecule Orally Available Checkpoint Inhibitor David Tuck, MD – Curis |
12:05 p.m. – 12:10 p.m. | LAG-3Ig (IMP321) in Combination with Anti-PD-1 Therapy Frederic Triebel, MD, PhD – Prima Biomed Ltd |
12:10 p.m. – 12:15 p.m. | Agent A - PD-1 DNR-41BB: Converting Tumor-Mediated PD-L1 Inhibition into CAR T-Cell Costimulation Prasad S. Adusumilli, MD, FACP, FCCP – Memorial Sloan Kettering Cancer Center |
12:15 p.m. – 12:20 p.m. | The Immunoreceptor TIGIT Regulates Anti-Tumor Immunity Jane Grogan, PhD – Genentech |
12:20 p.m. – 12:45 p.m. | Audience Question & Answer Adrian Bot, MD, PhD – Kite Pharma, Inc. |
Session III: Strategic Considerations of Combinations and Biomarkers in New Agent Development
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1:30 p.m. – 2:00 p.m. | Combinations & Biomarkers Charles G. Drake, MD, PhD – Columbia University Herbert Irving Comprehensive Cancer Center |
2:00 p.m. – 3:25 p.m. | Extended Panel Discussion Co-Chairs: Andrian Bot, MD, PhD – Kite Pharma, Inc. Daniel Chen, MD, PhD – Genentech Roger Dansey, MD – Merck & Co., Inc. Ramy Ibrahim, MD – Parker Institute for Cancer Immunotherapy (formerly at AstraZeneca) Salil Patel – Bristol-Myers Squibb Faculty: Raj K. Puri, MD, PhD – U.S. Food & Drug Administration Marc Theoret, MD – U.S. Food & Drug Administration Charles G. Drake, MD, PhD – Columbia University Herbert Irving Comprehensive Cancer Center Gordon J. Freeman, PhD – Dana-Farber Cancer Institute |
3:25 p.m. – 3:30 p.m. | Closing Remarks Roger Dansey, MD – Merck & Co., Inc. |
Important Dates
Regular Abstracts Published in JITC
November 8, 2016
Late-Breaking Abstracts Published in JITC
December 8, 2016
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