Wednesday, October 28
|
7:45 am - 7:50 am |
Welcome and Introduction
Bernard A. Fox, PhD - Earle A. Chiles Research Institute |
7:50 am - 8:00 am |
Biomarkers and the Critical Pathway Initiative
Samir Khleif, MD - National Cancer Institute |
8:00 am - 8:15 am |
FDA Perspective on Biomarkers
Steven Kozlowski, MD - Food and Drug Administration, Office of Biotechnology Products |
8:15 am - 8:25 am |
The Biomarkers Consortium: A Public-Private Partnership to Advance Biomarker Research
Shawnmarie Mayrand-Chung, PhD, JD - National Institutes of Health - Office of the Director, OPSA Public-Private Partnerships Program |
8:25 am - 10:30 am |
Session 1: Standardization and Validation of Immunologic Biomarkers
Co-Chairs: Mary (Nora) Disis, MD - University of Washington
Sylvia Janetzki, MD - ZellNet Consulting |
8:25 am - 8:55 am |
Standardization of Immune Biomarkers: Lessons from the HIV Field
Alan L. Landay, PhD - Rush University Medical Center |
8:55 am - 9:15 am |
Immune Monitoring Consortium Experience
Mary (Nora) Disis, MD - University of Washington |
9:15 am - 9:25 am |
Multi-Institution Trials and the Eastern Cooperative Oncology Group
Lisa H. Butterfield, PhD - University of Pittsburgh |
9:25 am - 10:30 am |
Discussion
Moderator: Sylvia Janetzki, MD - ZellNet Consulting
Discussants: Cedrik Britten, MD - Johannes Gutenberg University
Dominic Eisinger, PhD - Rules Based Medicine, Inc. |
10:30 am - 10:50 am |
Break |
10:50 am - 12:50 pm |
Session 2: Determining Potency of Immunologic Therapy
Co-Chairs: A. Karolina Palucka, MD, PhD - Baylor Institute for Immunology Research
Theresa Whiteside, PhD - University of Pittsburgh Cancer Institute |
10:50 am - 11:10 am |
Assessing Dendritic Cell Vaccines
A. Karolina Palucka, MD, PhD - Baylor Institute for Immunology Research |
11:10 am - 11:30 am |
Mechanisms of Immune Suppression and Regulatory T Cells
Theresa Whiteside, PhD - University of Pittsburgh Cancer Institute |
11:30 am - 11:50 am |
Use of Molecular Assays to Assess Cellular Therapies
David Stroncek, MD - Cell Processing, DTM, CC, National Institutes of Health |
11:50 am - 12:50 pm |
Discussion
Moderator: Licia Rivoltini, MD - Fondazione IRCCS Istituto Nazionale dei Tumori
Discussant: Edwin Walker, PhD - Providence Cancer Center |
12:50 pm - 1:20 pm |
Lunch |
1:20 pm - 3:20 pm |
Session 3: Assessing the Immunologic Signature of Clinical Response
Co-Chairs: Cedrik M. Britten, MD - Johannes Gutenberg University
Vernon C. Maino, PhD - BD Biosciences |
1:20 pm - 1:40 pm |
T Cell Response Signatures in Breast Cancer vs. Chronic Infection
Holden T. Maecker, PhD - Stanford University Medical Center |
1:40 pm - 2:00 pm |
Immunity to Glycolipid and Stem Cell Antigens in Human Cancer
Madhav Dhodapkar, MD - Yale University |
2:00 pm - 2:20 pm |
Summary of the US-Japan Workshop on Immunotherapy Markers in Oncology
Hideaki Tahara, MD, PhD - University of Tokyo |
2:20 pm - 3:20 pm |
Discussion
Moderator: Lupe G. Salazar, MD - University of Washington
Discussant: Keith Bahjat, PhD - Earle A. Chiles Research Institute |
3:20 pm - 3:45 pm |
Break |
3:45 pm - 4:45 pm |
Session 4: Centralization of Immunologic Monitoring
Co-Chairs: Alan L. Landay, PhD - Rush University Medical Center
Anatoli M. Malyguine, MD, PhD - SAIC-Frederick, NCI-Frederick |
3:45 pm - 3:55 pm |
Immunologic Monitoring of Cancer Vaccine Trials - What to Measure, How and Why?
Anatoli M. Malyguine, MD, PhD - SAIC-Frederick, NCI-Frederick |
3:55 pm - 4:25 pm |
System Biology Approaches
Rafick-Pierre Sékaly, PhD - University of Montreal, VGTI Florida |
4:25 pm - 4:45 pm |
Some Statistical Issues in the Design and Analysis of Vaccine Clinical Trials in Cancer Patients
Douglas M. Potter, PhD - University of Pittsburgh |
4:45 pm - 7:00 pm |
Session 5: Novel Marker Identification
Co-Chairs: Peter P. Lee, MD - Stanford University
Francesco Marincola, MD - National Institutes of Health |
4:45 pm - 5:00 pm |
High Throughput Technology and Predictive Immune Monitoring
Peter P. Lee, MD - Stanford University |
5:00 pm - 5:20 pm |
Systems Immunology at the Bedside
Damien Chaussabel, PhD - Baylor Institute for Immunology Research |
5:20 pm - 5:40 pm |
Trans-NIH Center for Human Immunology: Goals and Progress
Giorgio Trinchieri, MD - National Cancer Institute |
5:40 pm - 6:20 pm |
Application of Proteomics to Biomarker Discovery: New Challenges, New Technology
Lance Liotta, MD, PhD - George Mason University |
6:20 pm - 7:00 pm |
Defining Immunologic Health
Mark M. Davis, PhD - Howard Hughes Medical Institute / Stanford University School of Medicine |
7:00 pm |
Networking Reception |