iSBTc 25th Annual Meeting

Hot Topic Symposium:
CTLA-4 Blockade as a Cancer Therapeutic: How Do We Build on a Successful Foundation?

10:30am - 12:00pm
October 4, 2010
Hyatt Regency Washington on Capitol Hill
Washington, D.C.


Symposium Chair
James P. Allison, PhD
Memorial Sloan-Kettering Cancer Center

 

This cutting-edge session presented exciting new data on CTLA-4 blockade, including existing therapeutic combinations with anti-CTLA-4 that are poised for clinical use, potential future combinations, and insights into future directions in CTLA-4 blockade research and clinical translation.


Program Goals
  1. Present the latest pre-clinical and clinical data on CTLA-4 blockade in combination with other therapeutic agents.
  2. Explore future therapeutic combinations and clinical applications of CTLA-4 blockade for cancer treatment.
  3. Review clinical trial designs and biomarker endpoints to advance clinical translation of CTLA-4 blockade for cancer treatment.
  4. Explore directions for future research and application of CTLA-4 blockade in clinical oncology.
Intended Learner Outcomes
Upon completion of this meeting, participants will be able to:
  1. Discuss the latest clinical data on CTLA-4 blockade for cancer treatment.
  2. Identify promising therapeutic combinations with CTLA-4 blockade.
  3. Apply new considerations for clinical trial design and biomarkers in studies of CTLA-4 blockade.
  4. Identify productive new research directions to advance CTLA-4 blockade and improve cancer outcomes.

Schedule
To view slides from a presenter click the icon next to the presentation title.

10:30 am - 12:00 pm

Hot Topic Symposium:CTLA-4 Blockade as a Cancer Therapeutic: How Do We Build on a Successful Foundation?
10:35 - 10:55 am

Anti CTLA-4 Antibodies: Lessons Learned and Future Direction
Kevin Heller, MD - Bristol-Myers Squibb Company
10:55 - 11:15 am

Combination opportunities in immunotherapy with immunostimulatory mAb
Ignacio Melero, MD, PhD - University of Navarra
11:15 - 11:35 am

Exploring Therapeutic Combinations with Anti-CLTA-4 Antibody
Padmanee Sharma, MD, PhD - University of Texas, MD Anderson Cancer Center
11:35 am - Noon

Panel and Audience Discussion

 

Creative Commons License
All presentations are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

The Hot Topic Symposium is a non-accredited continuing medical education event. No credits are offered for physician participation in this educational program.