SITC Workshop Presentations

October 24-25, 2012
8:00 am - 5:00 pm
Bethesda North Marriott Hotel & Conference Center
North Bethesda, MD

Presentations are posted online based upon presenter approval.

Program Schedule

Wednesday, October 24

7:00 am - 8:00 am Registration and Continental Breakfast
Session 100: Keynote Address
8:00 am - 9:00 am Immunity in Cancer Growth and Progression
Nicholas P. Restifo, MD - National Cancer Institute
Session 101: Cells of the Immune System In the Tumor Microenvironment
9:00 am - 9:30 am Integrative Cancer Immunology: Importance of T Cells
Jerome Galon, PhD - INSERM- Cordeliers Research Center
9:30 am - 10:00 am T Lymphocytes in Human Melanoma Metastases
Pierre G. Coulie, MD, PhD - De Duve Institute and University of Louvain
10:00 am - 10:30 am Refreshments and Networking
Session 102: Stromal Elements of the Tumor Microenvironment
10:30 am - 11:00 am Endothelial Regulation of T cell Trafficking in Tumors
George Coukos, MD, PhD - University of Pennsylvania Medical Center
11:00 am - 11:30 am Immune Suppression by Stromal Cells PDF
David H. Munn, MD - Georgia Health Sciences University
11:30 am - 12:00 pm Relapse of Cancer: Stromal Cross-Presentation is Required for the
Elimination of Escape Variants

Hans Schreiber, MD, PhD - University of Chicago
12:00 pm - 1:30 pm Lunch Break and Networking
Session 103: Inflammation and Immune Trafficking
1:30 pm - 2:00 pm Innate and Adaptive Immunity Regulated Within the Tumor Microenvironment PDF
Thomas F. Gajewski, MD, PhD - University of Chicago
2:00 pm - 2:30 pm Chemotherapy Alters a Tolerogenic Environment in the Spleen of Tumor-
Bearing Hosts

Vincenzo Bronte, MD - University of Verona
2:30 pm - 3:00 pm An Experimentally Verified Quantitative Model and In Vitro Methods that Enable Cellular Immunotherapists to Calculate the Concentration of Cytolytically Active Immune Effector Cells Required to Produce Sterilizing Immunity in Neoplastic and Infectious Diseases
Samuel C. Silverstein, MD - Columbia University
3:00 pm - 3:30 pm Manipulating MDSC to Promote Regression
Dmitry I. Gabrilovich, MD, PhD - H. Lee Moffitt Cancer Center and Research Institute
Session 104: Keynote Address
3:30 pm - 4:30 pm Mechanisms of Protective Tumor Immunity
Glenn Dranoff, MD - Dana-Farber Cancer Institute

Thursday, October 25

7:00 am - 8:00 am Registration and Continental Breakfast
Session 200: Remodeling the Tumor Microenvironment to Promote Tumor Regression
8:00 am - 8:30 am Oncogene Inactivation and CD4+ T Cells PDF
Dean W. Felsher, MD, PhD - Stanford University School of Medicine
8:30 am - 9:00 am Immune Checkpoint Modulation and the Tumor Microenvironment
Drew M. Pardoll, MD, PhD - Johns Hopkins University School of Medicine
9:00 am - 9:30 am Immune Impact on Cancer Stemness and Metastasis PDF
Weiping Zou, MD, PhD - University of Michigan
9:30 am - 10:00 am Manipulating T Cells to Promote Regression
Laurence J.N. Cooper, MD, PhD - MD Anderson Cancer Center
10:00 am - 10:30 am Refreshments and Networking
Session 201: Monitoring Immune Responses with the Tumor Microenvironment
10:30 am - 11:00 am Microenvironment Immunogenetics Biomarkers in Combination
Immunotherapy
PDF

Samir N. Khleif, MD - Georgia Health Sciences University
11:00 am - 11:30 am Visualizing CTL and NK Cells Cytotoxic Activity in Solid Tumors
Philippe Bousso, PhD - INSERM U668
11:30 am - 12:00 pm Epigenetic Immune Cell Markers - Enabling Novel Clinical Trials with
Robust Results from Frozen Whole Blood or Tissue
PDF

Thomas O. Kleen, PhD - Epiontis GmbH
12:00 pm - 12:30 pm Immune Response Signatures and Patient Survival PDF
Mary L. Disis, MD - University of Washington
12:30 pm - 2:00 pm Lunch Break and Networking
Session 202: Clinical Trials: Provoking Immunity in the Tumor Microenvironment
2:00 pm - 2:30 pm Combination Immunotherapies Designed to Target the Tumor
Microenvironment
PDF

Leisha A. Emens, MD, PhD - Johns Hopkins University
2:30 pm - 2:50  pm MDSC Inhibition Augments Immune Function in Head and Neck Cancer Patients: Results of PDE5 Inhibition
Ivan Borrello, MD - Johns Hopkins University School of Medicine
2:50 pm - 3:10 pm Clinical Trials: Provoking Immunity in the Tumor Microenvironment PDF
Antoni Ribas, MD - UCLA Medical Center
3:10 pm - 3:30 pm Sunitinib and Immunity PDF
Brian I. Rini, MD - Cleveland Clinic Taussig Cancer Center
Session 203: Immunoscore
3:30 pm - 3:50 pm The Immunoscore: A Proposal for a New Classification of Cancer in the Era of Immunotherapies
Jerome Galon, PhD - INSERM- Cordeliers Research Center
3:50 pm - 4:10 pm The Impact of Immune Cell Infiltration on Patient Prognosis
Alessandro Lugli, MD - Institut of Pathology University of Bern
4:10 pm - 4:30 pm A Strategic View of the Immunoscore PDF
Bernard A. Fox, PhD - Earle A. Chiles Research Institute
4:30 pm - 4:50 pm Immune System and Cancer: Importance of the Immunoscore PDF
Francesco Marincola, MD - National Institutes of Health
4:50 pm - 5:00 pm Closing Comment

Creative Commons License
All presentations are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

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  • October 28, 2012
    SITC Hot Topic Symposium: PD-1/PD-L1: Right on Target
     

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