Abstract Titles
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All accepted abstracts will be available in the Journal for ImmunoTherapy of Cancer (JITC).
Abstract Titles
Onsite Posters
Onsite posters will be presented in the Poster Hall at the Walter E. Washington Convention Center in Washington, D.C. All odd numbered posters will be presented on Friday, Nov. 12, 2021. Even numbered posters will be presented Saturday, Nov. 13, 2021.
ePosters
ePosters will be on display on the SITC 2021 virtual meeting platform from 7 a.m. EST on Friday, Nov. 12, 2021 until the virtual meeting platform is closed on Jan. 9, 2022.
| # | Type | Title | Authors | Category | Keywords |
|---|---|---|---|---|---|
| 682 | Poster Presentation | PKC Agonism Restricts Innate Immune Suppression, Promotes Antigen Cross-Presentation and Synergizes with Agonistic CD40 Therapy in Breast Cancer | Mehdi Chaib, MS; Liza Makowski; John Yarbro; Laura Sipe; Deidre Daria | Immune Cell Types | Antigen presenting cells;Dendritic cell;Immune suppression;MDSC;Monocyte/Macrophage;Myeloid cells;Solid tumors;T cell;T cell lineages;Tumor microenvironment |
| 683 | Oral Presentation | Type-I-interferon activates cross-dressed CD11b+ conventional dendritic cells to enhance anti-tumor immunity | Ellen Duong, Sc.B.; Timothy Fessenden, Ph.D.; Emi Lutz; Teresa Dinter; Leon Yim; Sarah Blatt; Arjun Bhutkar; K. D. Wittrup; Stefani Spranger, PhD | Immune Cell Types | Antigen presenting cells;Costimulation;Cytokine;Dendritic cell;Myeloid cells;T cell;Tumor infiltrating lymphocytes (TILs);Tumor microenvironment |
| 684 | Poster Presentation | The in vitro effects of 5-Azacitidine on the immunophenotype of monocyte-derived dendritic cells from patients with higher-risk myelodysplastic syndromes | Randy G. Tsai, BS, BA; Hannah Fields, BS; Xinlian Zhang, PhD; Valentina Ferrari, BA; Soo J. Park, MD; Rafael Bejar, MD, PhD; Tiffany Tanaka, MD | Immune Cell Types | Antigen presenting cells;Dendritic cell |
| 685 | Poster Presentation | Characterization of molecular and spatial diversity of macrophages in hepatocellular carcinoma | Pauline Hamon, PhD; Assaf Magen, PhD; Joel Kim; Mark Buckup; Leanna Troncoso; Steven Hamel; Jessica Le Berichel; Oren Barboy; Eyal David; Alexandra Tabachnikova; Christie Chang; Zhen Zhao; Merav Cohen, PhD; Amir Giladi; Nausicaa Malissen; Fiona Desland; Ido Amit; Ephraim Kenigsberg; Myron E. Schwartz, MD; Thomas U. Marron, MD, PhD; Miriam Merad, MD, PhD | Immune Cell Types | Antigen presenting cells;Checkpoint blockade;Clinical trial;Dendritic cell;Gene expression;Monocyte/Macrophage;Myeloid cells;Solid tumors;Tumor microenvironment |
| 686 | Poster Presentation | Characterization of a Novel Compound that Inhibits Peroxynitrite Generation by Myeloid Derived Suppressor Cells | Gabriella N. Lapurga, BS; Steven H. Sun; Erick Carlson; Himanshu Savardekar, BS; Kari Kendra, MD; Blake Peterson; William E. Carson, III, MD, FACS | Immune Cell Types | Antibody;Checkpoint blockade;Immune suppression;Inflammation;MDSC;Solid tumors;T cell;Tumor microenvironment |
| 687 | Poster Presentation | MDSC gene expression analysis in patients with cancer and the response to inhibition of Bruton’s tyrosine kinase | Himanshu Savardekar, BS; Carter Allen, BS; Dionisia Quiroga, DO/PhD; Donjun Chung, PhD; Emily Schwarz, BS; Gabriella N. Lapurga, BS; Jami Shaffer, BS; Bradley Blaser, MD/PhD; Matthew Old, MD; Robert Wesolowski, MD; Kari Kendra, MD; William E. Carson, III, MD, FACS | Immune Cell Types | Bioinformatics;Chemokine;Cytokine;Gene expression;Granulocyte;MDSC;Monocyte/Macrophage;Myeloid cells |
| 688 | Poster Presentation | Knockout of the inhibitory receptor TIGIT enhances anti-tumor response of ex vivo expanded NK cells | Tayler J. Croom-Perez, PhD; Md Faqrul Hasan, Masters; Thomas A. Dieffenthaller; Liza D. Robles-Carrillo; Jonathan E. Eloriaga; Alicja J. Copik, PhD | Immune Cell Types | Adoptive immunotherapy;NK/NKT cell |
| 689 | Poster Presentation | Tissue-specific anti-tumor NK cell activation & effector functions | Zerick T. Dunbar, MS; Anil Shanker, PhD | Immune Cell Types | Bioinformatics;Cytokine;NK/NKT cell;Solid tumors;Tumor microenvironment |
| 690 | Poster Presentation | TIGIT blockade improves anti-tumor activity of ex vivo expanded NK cells | Md Faqrul Hasan, Masters; Alicja J. Copik, PhD | Immune Cell Types | Adoptive immunotherapy;Checkpoint blockade;NK/NKT cell |
| 691 | Poster Presentation | Identification of shared tumor epitopes from endogenous retroviruses inducing high avidity cytotoxic T cells for cancer immunotherapy | Paola Bonaventura, PhD; Vincent Alcazer, MD; Virginie Mutez; Laurie Tonon; Juliette Martin, PhD; Nicolas Chuvin, PhD; Rasha Boulos, PhD; Yann Estornes, PhD; Jenny Valladeau-Guilemond, PhD; Alain Viari, PhD; Christophe Caux, PhD; Stephane Depil, MD, PhD | Immune Cell Types | Antigen presenting cells;Bioinformatics;Dendritic cell;Neoantigens;Solid tumors;T cell;TLR;Tumor antigens;Tumor infiltrating lymphocytes (TILs);Vaccine |
| 692 | Poster Presentation | Tim-3 expression drives phenotypic and functional changes in Treg in secondary lymphoid organs and the tumor microenvironment, effecting tumor burden. | Hridesh d. Banerjee, PhD; Hector Nieves-Rosado, MDPHD(MSTP) candidate; Benjamin M. Murter, BS; Lawrence P. Kane, PHD | Immune Cell Types | Costimulation;Cytokine;Immune suppression;Metabolism;Regulatory T cell (Treg cell);T cell;T cell lineages;Tumor evasion;Tumor infiltrating lymphocytes (TILs);Tumor microenvironment |
| 693 | Oral Presentation | Mucosal-Associated Invariant T (MAIT) Cell Regulation Networks in Anti-Tumor Immunity | Benjamin Ruf, M.D.; Vanessa V. Catania, B.A.; Noemi Kedei, MD; Simon Wabitsch, M.D.; Chi Ma, MD, PhD; Laurence P. Diggs, M.D.; Qianfei Zhang, PhD; Bernd Heinrich, MD; Varun Subramanyam, B.A.; Linda Cui, B.A.; Shunsuke Sakai, PhD; Sangmi Oh, Ph.D.; Merrill K. Stovroff, B.A.; Clifton E. Barry III, Ph.D.; Daniel E. Barber, Ph.D.; Alexander Kroemer, M.D.; Firouzeh Korangy, Ph.D.; Tim F. Greten, MD | Immune Cell Types | Solid tumors;T cell;TLR;Tumor microenvironment |
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