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All accepted abstracts are available in the Journal for ImmunoTherapy of Cancer (JITC).

Abstract Titles

Poster Presentation Dates

All odd numbered posters will be presented on Wednesday, Nov. 11, from 5:15-5:45 p.m. EST and Friday, Nov. 13, from 4:40-5:10 p.m. EST. Even numbered posters will be presented on Thursday, Nov. 12, from 4:50-5:20 p.m. EST and Saturday, Nov. 14, from 1-1:30 p.m. EST.

Posters will be on display from 8 a.m. on Monday, Nov. 9, until the virtual poster hall closes on December 31, 2020.


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# Type Title Authors Category Keywords
732 Poster Presentation Chemerin reactivates PTEN and suppresses PD-L1 in tumor cells via a novel CMKRL1-mediated pathway Russell Pachynski, MD; Keith R. Rennier, PhD; Woo Jae Shin; Ethan Krug; Gurpal Virdi, BS; Russell Pachynski, MD; Tumor and Stromal Cell Biology Chemokine; Cytokine; Gene expression; Solid tumors; Tumor evasion
733 Poster Presentation Integrative molecular profiling of high-grade primary prostate cancer identifies patients with a biomarker profile that favors the combination of standard of care (SOC) therapy with immunotherapy Evisa Gjini, PhD; Jimena Trillo-tinoco; Andrew Browne; Ryan Powles; Tai Wang; Christine Tauras; Ana Lako; Ruben Ferrer-Luna; Zoe Bleicher; timothy consedine; Chensheng Zhou; Evan Kelemen; anne lewin; Catherine King; sumit bhattacharya; harris bell-temin; ashok dongre; David Nelson; Christos Hatzis, PhD; Kenzie Macisaac; Fadi Towfic; Benjamin Chen, MD, PhD; Michaela Bowden, PhD; Evisa Gjini, PhD; Tumor and Stromal Cell Biology Biomarkers; Gene expression; Immune suppression; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma
734 Poster Presentation A novel NQO1 specific anti-tumor agent, SBSC-S3001, selectively regresses the growth of tumors with high NQO1 expression. Minhyuk Yun; Goo-Young Kim, Ph.D.; Sang Woo Jo; Changhoon In; Gyu-Young Moon; In Seok Ko; Eun Ju Lee; Yong Rae Hong; Whee Seong Lee; Helen Cho; Tumor and Stromal Cell Biology Chemotherapy; Gene expression; Immune monitoring; Metabolism
735 Poster Presentation Impact of reversing an epithelial-to-mesenchymal transition program on tumor metabolism and immune suppression Michelle M. Williams, Ph.D.; Jessica L. Christenson, Ph.D.; Kathleen I. O'Neill; Sabrina A. Hafeez; Nicole S. Spoelstra; Jill E. Slansky, PhD; Jennifer K. Richer, Ph.D.; Tumor and Stromal Cell Biology Immune suppression; Monocyte/Macrophage; Metabolism; Solid tumors; Tumor evasion
736 Poster Presentation MicroRNA expression patterns in melanomas originating from gynecologic sites Mallory J. DiVincenzo, DVM; Lorena Suarez-Kelly, MD; Maribelle Moufawad; Casey Ren; Zoe Barricklow; Paolo Fadda, PharmD; Lianbo Yu, PhD; Sarah Peters, MD; Alejandro A. Gru, MD; William E. Carson, III, MD, FACS; Tumor and Stromal Cell Biology Bioinformatics; Biomarkers; Cytokine; Epigenetics; Gene expression; RNA
737 Poster Presentation A novel humanized murine model to identify neoantigen-specific T cells in pediatric acute megakaryoblastic leukemia. Elizabeth A. Garfinkle, BS; Anthony E. Zamora, PhD; Jeremy C. Crawford, PhD; Paul G. Thomas, PhD; Tanja A. Gruber, MD, PhD; Tumor and Stromal Cell Biology Adoptive immunotherapy; Bioinformatics; Cytokine; Leukemia/Lymphoma; Neoantigens; T cell; Tumor infiltrating lymphocytes (TILs)
738 Poster Presentation Establishment and application of a series of genetically engineered mouse derived breast cancer homograft models Yanrui Song; Jessie J. Wang; Likun Zhang; Annie X. An; Henry Q. Li; Davy X. Ouyang, PhD; Tumor and Stromal Cell Biology Carcinogenesis; Immune monitoring; Solid tumors; Tumor microenvironment
739 Poster Presentation Development of Patient-Derived Models of Esophageal Cancer for GUCY2C-Directed Immunotherapeutic Testing Megan Weindorfer, BS; Amanda N. Lisby, MS; Alicja Zalewski, MD; Trevor R. Baybutt, BA; Robert Carlson, BS; Madison Crutcher, MD; David Loren, MD; Ernest Rosato, MD; Nathaniel Evans III, MD; Scott A. Waldman, MD, PhD; Adam E. Snook, PhD; Tumor and Stromal Cell Biology Adoptive immunotherapy; CAR T cells; Carcinogenesis; Targeted therapy
740 Poster Presentation Biomarkers Diverging between Tumor Mutation Burden and Microsatellite Instability Jason Ding; Nihir Patel; Tumor and Stromal Cell Biology Bioinformatics; Biomarkers; Carcinogenesis; Epigenetics; Gene expression; Systems biology
741 Poster Presentation High-grade sinonasal carcinomas and surveillance of differential expression in immune related transcriptome Diana Bell; Achim Bell, PhD; Renata Ferrarotto, MD; Ehab Hanna; Diana Bell; Tumor and Stromal Cell Biology Inflammation; Solid tumors; Tumor antigens; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment
742 Poster Presentation Phosphopeptides are Increased in the MHC-I Immunopeptidome of Irradiated Human Breast Cancer Cells Samantha J. Van Nest, PhD, MS; Tomer M. Yaron; Martin G. Klatt; Noah Dephoure; Gad Getz, PhD; Laura Santambrogio; Olivier Elemento, PhD; David A. Scheinberg; Sandra Demaria, MD; Lewis C. Cantley; Tumor and Stromal Cell Biology Proteomics; Radiotherapy; Tumor antigens; Post-translational modifications
743 Poster Presentation High levels of stromal tumor infiltrating lymphocytes, CD3, CD8 cells & Immunoscore® are associated with pathological CR and time to progression in TNBC patients undergoing neo-adjuvant chemotherapy. Bernardo L. Rapoport, MD, MMed; Jérôme Galon; Simon Nayler; Aurelie Fugon; Isabelle Boquet; Marine Martel; Mlecnik B; Teresa Smit; Carol Ann Benn; Farhana Moosa; Liezl Heyman; Ronald Anderson, Prof; Tumor and Stromal Cell Biology Biomarkers; Chemotherapy; Immune monitoring; Immune suppression; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma
744 Oral Presentation Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy Hussein Abbas; Dapeng Hao, Ph.D.; Katarzyna J. Tomczak; Praveen Barrodia; Jin Seon Im; Patrick Reville; Zoe Alaniz; Wei Wang; Ruiping Wang; Feng Wang, PhD; Gheath Al-Atrash; Koichi Takahashi, MD; Jing Ning; Maomao Ding; Jairo Matthews; Latasha Little, BS; Jianhua Zhang; Sreyashi Basu; Marina Konopleva; Guillermo Garcia-Manero, MD; Michael R. Green, PhD; Padmanee Sharma, MD, PhD; James P. Allison, PhD; Steven M. Kornblau, MD; Kunal Rai; Linghua Wang, PhD; Naval Daver, MD; Andrew Futreal; Tumor and Stromal Cell Biology Bioinformatics; Checkpoint blockade; Immune contexture; Immune monitoring; Immune tolerance; Leukemia/Lymphoma; T cell; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment
745 Poster Presentation High throughput tissue imaging and phenotyping by streamlined 8-plex staining and analysis of complex TMA samples Amanda J. Bares, PhD; Marie Cumberbatch; Lorcan Sherry, PhD; Christopher Womack; Milan Bhagat; Angela Vasaturo, PhD; Mael Manesse, PhD; Tumor and Stromal Cell Biology Antibody; Biomarkers; Immune contexture; Immune monitoring; Solid tumors; Tumor evasion; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma
746 Poster Presentation Non Small-Cell Lung Cancer cells and cancer-associated fibroblasts drive macrophage polarization in a novel co-culture model Josiah Flaming, B.S.; Raghav Chandra; Luc Girard, Ph.D.; Debolina Ganguly, M.S.; Jason Toombs, B.S.; John D. Minna, M.D.; Rolf A. Brekken, Ph.D.; Tumor and Stromal Cell Biology Cytokine; Gene expression; Immune suppression; Immune tolerance; Inflammation; Monocyte/Macrophage; Solid tumors; Tumor evasion; Tumor microenvironment; Tumor stroma
747 Poster Presentation Evaluation of immune microenvironment of primary lung cancer and synchronous liver metastasis with multispectral imaging system Hyeonbin Cho; Jae-Hwan Kim, PhD; Ji-Hyun Kim; Tumor and Stromal Cell Biology Biomarkers; Regulatory T cell (Treg cell); T cell; Tumor infiltrating lymphocytes (TILs); Tumor antigens; Tumor microenvironment; Tumor stroma
748 Poster Presentation Myeloid Cell Infiltration Correlates with Prognosis and Varies Based on Tumor Location in Cholangiocarcinoma Sean C. Dougherty, MD; Paul R. Kunk, MD; Sean C. Dougherty, MD; Tumor and Stromal Cell Biology Antigen presenting cells; Dendritic cell; Monocyte/Macrophage; Myeloid cells; Solid tumors; T cell; Targeted therapy; Tumor antigens; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment
749 Poster Presentation Spatial profiling of the tumour microenvironment in head and neck cancer to identify biomarkers of response to therapy Arutha J. Kulasinghe, PhD; Tumor and Stromal Cell Biology Biomarkers; Checkpoint blockade; Solid tumors; T cell; Tumor evasion; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma
750 Poster Presentation Malat1 lncRNA Controls Metastatic Reactivation of Dormant Breast Cancer by Immune Evasion Dhiraj Kumar, PhD; Sreeharsha Gurrapu, PhD; Hyunho Han, MD, PhD; Yan Wang, MD, PhD; Seongyeon Bae, PhD; Hong Chen, PhD; Chang-Jiun Wu, PhD; Filippo Giancotti, MD, PhD; Tumor and Stromal Cell Biology Immune monitoring; Immune toxicity; Inflammation; MDSC; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; RNA
752 Poster Presentation The impact of grade of differentiation and BRAF mutation status on neoantigen and immune landscape in papillary thyroid cancer Myungwoo Nam, MD; Woojung Yang; Ju Young Lee, MD; Jaeyoun Choi, M.D.; Hansol Choi; Emma Yu; Eugene Kim; Jin Young Hwang; William H. Bae; Chan Mi Jung; Victor Wang; Jeffrey Chuang; Young Kwang Chae; Tumor and Stromal Cell Biology Gene expression; Neoantigens; Regulatory T cell (Treg cell); T cell; Tumor antigens; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment
753 Poster Presentation The immune landscape of papillary thyroid cancer and its association with neoantigen landscape and DNA repair gene mutations Myungwoo Nam, MD; Woojung Yang; Ju Young Lee, MD; Jaeyoun Choi, M.D.; Hansol Choi; Eugene Kim; Emma Yu; Jin Young Hwang; William H. Bae; Chan Mi Jung; Victor Wang; Jeffrey Chuang; Young Kwang Chae; Tumor and Stromal Cell Biology Gene expression; Neoantigens; Regulatory T cell (Treg cell); T cell; Tumor antigens; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment
754 Poster Presentation Dysregulation of soluble immune checkpoint proteins in newly - diagnosed early breast cancer patients. Bernardo L. Rapoport, MD, MMed; Helen Steel; Simon Nayler; Teresa Smit; Liezl Heyman; Annette Theron; Nomsa Hlatswayo; Luyanda Kwofie; Carol Ann Benn; Lidia jooste; Ronald Anderson, Prof; Tumor and Stromal Cell Biology Biomarkers; Chemokine; Chemotherapy; Costimulation; Cytokine; Immune suppression; Solid tumors; Tumor microenvironment
755 Oral Presentation CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity Alvaro Teijeira; Saray Garasa, BS; Itziar Migueliz; Assunta Cirella; Ignacio J. Melero, Dr., MD, PhD; Alvaro Teijeira; Tumor and Stromal Cell Biology Chemokine; Granulocyte; Myeloid cells; MDSC; Tumor microenvironment
756 Poster Presentation Assessment of the immune checkpoint landscape in head and neck squamous cell carcinoma by single-cell RNA sequencing and multispectral imaging Lazar Vujanovic, PhD; Aditi Kulkarni; Cornelius Kürten, MD; Anthony R. Cillo, PhD; Patricia M. Santos, PhD; Stephan Lang; Uma Duvvuri, MD PhD.; Seungwon Kim, MD; Heath Skinner; Tullia C. Bruno, PhD; Dario A. Vignali, PhD; Riyue Bao, PhD; Robert L. Ferris, MD, PhD; Tumor and Stromal Cell Biology Gene expression; Immune contexture; Immune suppression; Inflammation; Monocyte/Macrophage; Myeloid cells; Solid tumors; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma

Late-Breaking

864 Poster Presentation The mesenchymal stromal compartment in colorectal cancer greatly alters the innate tumour immune microenvironment both in 2D and 3D culture systems Niamh A. Leonard, MSc; Oliver Treacy, PhD; Hannah Egan, BSC; Grace O'Malley; Elena Tomas Bort; Eleonora Peerani; Thomas Ritter, Prof.; Daniela Loessner; Laurence J. Egan, MD; Aideen E. Ryan, PhD; Tumor and Stromal Cell Biology Antigen presenting cells; Cytokine; Immune suppression; Inflammation; Monocyte/Macrophage; Solid tumors; Tumor infiltrating lymphocytes (TILs); Tumor stroma
865 Poster Presentation Sugar high: Does the sialic acid profile of cancer-associated fibroblasts induce a more tumour-permissive microenvironment? Hannah Egan, BSC; Niamh A. Leonard, MSc; Kevin Lynch, PhD; Oliver Treacy, PhD; Amir Nader; Margaret Sheehan, Dr; Sean Hynes, Dr; Laurence J. Egan, MD; Thomas Ritter, Prof.; John Daly; Aisling Hogan, Dr.; Michael O; Aideen E. Ryan, PhD; Tumor and Stromal Cell Biology Immune suppression; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma
867 Poster Presentation Distinct genomic features across cytolytic subgroups in skin melanoma Apostolos Zaravinos; Constantinos Roufas; Ilias Georgakopoulos-Soares; Tumor and Stromal Cell Biology Bioinformatics; Checkpoint blockade; Gene expression; Immune contexture; Immune suppression; Immune toxicity; Tumor antigens; Tumor evasion
868 Poster Presentation PRELP-facilitated enhancement of MHC class I surface expression in B16F10 melanoma cells Helene Schäfer, none; Karthikeyan Subbarayan, MSc; Barbara Seliger, MD, PhD; Tumor and Stromal Cell Biology Antigen presenting cells; Bioinformatics; Biomarkers; Gene expression; Solid tumors; Tumor antigens; Tumor evasion; Tumor microenvironment; Tumor stroma
869 Oral Presentation Anti-LunX targeting therapy for lung cancer Xiaohu Zheng; Weihua Xiao, MD, MS; Zhigang Tian, MD, PhD; Tumor and Stromal Cell Biology Antibody; Targeted therapy; Tumor antigens
870 Poster Presentation Investigating sexual dimorphism in the tumor immune microenvironment of non-muscle invasive bladder cancer Stephen Chenard, BScH; Stephen Chenard, BScH; Chelsea Jackson, PhD; Thiago Vidotto, MSc, PhD; Celine Hardy, BScH; Tamara Jamaspishvilli, MD, PhD; David Berman, MD, PhD; David Robert Siemens, MD; Madhuri Koti, DVM, MVSc, PhD; Tumor and Stromal Cell Biology B cell; Biomarkers; Gene expression; Immune contexture; Immune suppression; Monocyte/Macrophage; Tumor microenvironment; Tumor stroma
871 Poster Presentation In Vitro immunoregulatory effect from Cervical Cancer derived Mesenchymal Stromal Cells over molecules expression in Monocyte derived Macrophage polarization. Víctor A. Cortrés-Morales; Juan J. Montesinos; Luis Chávez-Sánchez; Sandra Espíndola-Garibay; Alberto Monroy-García; Teresa Apresa-García; Héctor Mayani; Tumor and Stromal Cell Biology Monocyte/Macrophage; Solid tumors; Tumor microenvironment
872 Poster Presentation Neoadjuvant chemoradiotherapy enhances T cell infiltration in pancreatic ductal adenocarcinoma but high percentage of regulatory T cells associates with poor survival Benjamin T. Fullerton, BA; Robyn D. Gartrell, MD; Thomas Enzler, MD PhD; Pan S. Kim, MD; Ladan Fazlollahi, MD, MPH; Andrew X. Chen, BS; Subha Perni, MD; Stuart P. Weisberg, MD, PhD; Emanuelle M. Rizk; Eun Jeong Oh; Xinzheng Guo; Codruta Chiuzan, PhD; Raul Rabadán, PhD; Donna Farber, PhD; Helen E. Remotti, MD; David P. Horowitz, MD; Yvonne M. Saenger, MD; Tumor and Stromal Cell Biology Chemotherapy; Radiotherapy; Regulatory T cell (Treg cell); T cell; Tumor microenvironment
873 Poster Presentation Pharmacologic macrophage depletion affects metastasis formation by modulating systemic immune responses in a genetic pancreatic cancer model Heidi Griesmann, PhD; Christof Drexel; Nada Milosevic; Bence Sipos; Thomas Gress; Patrick Michl; Tumor and Stromal Cell Biology Angiogenesis; Carcinogenesis; Monocyte/Macrophage; Regulatory T cell (Treg cell); Solid tumors; Tumor microenvironment