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All accepted abstracts are available in the Journal for ImmunoTherapy of Cancer (JITC).
Abstract Titles
Poster Presentation Dates
All odd numbered posters will be presented on Wednesday, Nov. 11, from 5:15-5:45 p.m. EST and Friday, Nov. 13, from 4:40-5:10 p.m. EST. Even numbered posters will be presented on Thursday, Nov. 12, from 4:50-5:20 p.m. EST and Saturday, Nov. 14, from 1-1:30 p.m. EST.
Posters will be on display from 8 a.m. on Monday, Nov. 9, until the virtual poster hall closes on December 31, 2020.
| # | Type | Title | Authors | Category | Keywords |
|---|---|---|---|---|---|
| 492 | Poster Presentation | Integration of high dimensional datasets in an immunocompetent mammary mouse model reveals pathways of tolerance and resistance to immune checkpoint blockade | Jade Moore, PhD; Lin Ma, PhD; Jian-Hua Mao, PhD; Mary Helen Barcellos-Hoff, PhD; | Immune Cell Biology | Checkpoint blockade; Gene expression; Immune monitoring; Inflammation; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 493 | Poster Presentation | Tired and Hungry: A potential role for CD47 in T cell exhaustion | Chien-Huan Weng, PhD; Levi M. Mangarin, BS; Cailian Liu, MD; Roberta Zappasodi, PhD; Pamela M. Holland, PhD; Jedd D. Wolchok, MD, PhD; Taha Merghoub, PhD; David Schroder, MD; | Immune Cell Biology | Adoptive immunotherapy; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 495 | Poster Presentation | Basal Cell Carcinoma demonstrates a T-cell exclusion immune phenotype in contrast to other anti-PD-1 therapy responsive cutaneous malignancies | Geoffrey T. Gibney, MD; Joanne Xiu; Gino K. In, MD, MPH; Steven J. O'Day, MD; Jose Lutzky, MD, FACP; Joseph J. Drabick, MD, FACP, FIDSA; Ari M. VanderWalde, MD, MPH, MBioeth; Kelsey Poorman; W. M. Korn; Michael B. Atkins, MD; | Immune Cell Biology | Angiogenesis; Biomarkers; Checkpoint blockade; Gene expression; Immune suppression; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 496 | Poster Presentation | Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features | Bradley Garman, MSc; Laurence Menard, PhD; Can Jiang, MSc; Sherif Daouti, MSc; Priyanka Mehta, MSc; Miye Jacques, MSc; Mohan Bolisetty, PhD; Christos Hatzis, PhD; Nataly Manjarrez Orduno, PhD; Michaela Bowden, PhD; Justin M. David, PhD; Justin M. David, PhD; Justin M. David, PhD; | Immune Cell Biology | Immune contexture; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 497 | Poster Presentation | Longitudinal immune profiling reveals unique myeloid and T cell phenotypes associated with spontaneous immunoediting in a novel prostate tumor model | Casey R. Ager, PhD; Aleksander Obradovic; Juan M. Arriaga, PhD; Matthew G. Chaimowitz; Cory Abate-Shen, PhD; Andrea Califano, PhD; Charles G. Drake, MD, PhD; | Immune Cell Biology | Dendritic cell; Granulocyte; Immune contexture; Immune monitoring; Monocyte/Macrophage; Myeloid cells; Regulatory T cell (Treg cell); T cell; Tumor evasion; Tumor microenvironment |
| 498 | Poster Presentation | Downregulation of CD5 in CD8+ T tumour-infiltrating lymphocytes associates with increased level of activation and exhaustion | Faizah Alotaibi; Mark D. Vincent, MD, FRCPC, MRCPUK; Weiping Min; James Koropatnick; | Immune Cell Biology | Checkpoint blockade; Immune suppression; Immune tolerance; T cell; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 499 | Poster Presentation | AT1636, a colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin. | Tim Beaumont, PhD; Martijn Kedde, PhD; Sabrina J. Merat, MSc; Mark J. Kwakkenbos, PhD; Lina Bartels; Dorien van der Berg; Koen Wagner, PhD; Arjen Q. bakker; Kelly Maijoor; Martino Bohne; Camille Bru; Veronika Kattler; Yvonne Claassen; Gemma Moiset, PhD; Hans Van Eenennaam, PhD; Victorine Roos; Frank Kallenberg; Jan P. Medema; Paul J. Hensbergen; Pauline M. van Helden, PhD; Evelien Dekker; Hergen Spits, PhD; | Immune Cell Biology | Antibody; B cell; Bispecifics; Post-translational modifications; Solid tumors; Targeted therapy; Tumor antigens |
| 500 | Poster Presentation | P2RX7 agonist treatment boosts the ability of IL-12-activated CD8+ T cells to infiltrate and control murine melanoma | Kelsey M. Wanhainen; Stephen C. Jameson; Henrique Borges Da Silva, PhD; | Immune Cell Biology | Adoptive immunotherapy; Immune adjuvant; Metabolism; T cell; Tumor infiltrating lymphocytes (TILs) |
| 501 | Poster Presentation | VISTA regulates the differentiation and suppressive function of myeloid-derived suppressor cells | Juan Dong, MD; Cassandra Gilmore; Hieu M. Ta, PhD; Keman Zhang; Sarah Stone; Li Wang, PhD; | Immune Cell Biology | Antibody; Immune suppression; MDSC; Myeloid cells; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 502 | Poster Presentation | The co-expression of two immune complex molecules, VISTA and TIGIT, define a dysfunctional cytotoxic T cell subset | Cassandra K. Gilmour, BS; Li Wang, PhD; Juan Dong, MD; Hieu M. Ta, PhD; | Immune Cell Biology | Biomarkers; Checkpoint blockade; Costimulation; Immune suppression; T cell; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 503 | Poster Presentation | Tumor infiltrating lymphocytes in soft tissue sarcomas upregulate the exhaustion marker TIGIT and are reinvigorated by IL-15 stimulation and TIGIT blockade | Sean J. Judge, MD, MS; Morgan A. Darrow, MD; Steven W. Thorpe, MD; Alicia A. Gingrich, MD; Edmond F. O'Donnell, MD; Alyssa R. Bellini, MD; Ian R. Sturgill; Logan V. Vick; Cordelia M. Dunai, MS; Kevin M. Stoffel, MS; Yue M. Lyu; Shuai M. Chen, PhD; May M. Cho, MD; Robert M. Rebhun, DVM PhD; Arta M. Monjazeb, MD, PhD; William J. Murphy, PhD; Robert J. Canter, MD, MAS, FACS; | Immune Cell Biology | NK/NK T cell; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 504 | Poster Presentation | Using multiplexed immunofluorescence to quantitatively analyze myeloid derived suppressor cells (MDSCs) in relation to tertiary lymphoid structures (TLS) in bladder cancer | Anna Juncker-Jensen, PhD; Gang Huang; Mate L. Nagy; Xin Lu; Anna Juncker-Jensen, PhD; Anna Juncker-Jensen, PhD; | Immune Cell Biology | Adoptive immunotherapy; B cell; Immune contexture; Immune suppression; MDSC; Monocyte/Macrophage; Myeloid cells; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma |
| 505 | Poster Presentation | Activation of NK T cells promote the inflammatory tumor microenvironment and control the growth of solid tumor | Sourav Paul, PhD; Amrita Mishra, MSc; Sushanta Chhatar; Girdhari Lal, PhD; Girdhari Lal, PhD; | Immune Cell Biology | Chemotherapy; Costimulation; Cytokine; Immune adjuvant; Inflammation; NK/NK T cell; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 507 | Poster Presentation | High dimensional flow cytometry analysis in newly diagnosed acute myeloid leukemia predicts patients outcomes | Francesco Mazziotta, MD; Rupkatha Mukhopadhyay; Hanna A. Knaus; Anish Chowdhury; Amanda Blackford; Ivana Gojo, MD; Leo Luznik, MD; | Immune Cell Biology | Bioinformatics; Chemotherapy; Immune contexture; Immune monitoring; Leukemia/Lymphoma; T cell; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 508 | Poster Presentation | Different neoantigen expression patterns impact the strength of anti-tumor immune responses | Kim B. Nguyen, B.A.; Stefani Spranger, PhD; Christopher J. Copeland, B.S.; | Immune Cell Biology | Immune suppression; Neoantigens; T cell; Tumor infiltrating lymphocytes (TILs) |
| 509 | Poster Presentation | Potent And Selective Inhibition Of AXL Receptor Tyrosine Kinase For The Treatment of Cancer | Susan L. Paprcka, PhD; Akshata R. Udyavar, Ph.D; Subhasree Sridhar; Dillon H. Miles, PhD; Yu Chen, PhD; Sean Cho, PhD; Corinne N. Foley, PhD; Rebecca Grange, PhD; Manmohan R. Leleti, PhD; Sharon Zhao, PhD; Lixia Jin, PhD; Stephen W. Young, PhD; Jay P. Powers, PhD; Matthew J. Walters, PhD; | Immune Cell Biology | Dendritic cell; Gene expression; Immune suppression; Immune tolerance; Monocyte/Macrophage; Myeloid cells; NK/NK T cell; Solid tumors; Targeted therapy; Tumor microenvironment |
| 510 | Poster Presentation | Helping the killers: innovative cancer immunotherapy harnessing quasi-universal tumor antigen-specific CD4 T cells | Margaux Saillard; Amelie Cachot; Georg Alexander Rockinger; Philippe Guillaume; Julien Schmidt, PhD; Alexandre Harari, PhD; Camilla Jandus, MD, PhD; Pedro J. Romero, MD; | Immune Cell Biology | Antigen presenting cells; T cell; Tumor antigens; Vaccine |
| 511 | Poster Presentation | Tumor immune microenvironment in adult mice asynchronously cross-fostered as pups | Vianca Vianzon, BS; Ishita Garg; Kara G. Greenfield; Kathryn A. Knoop, PhD; Laura M. Rogers, PhD; | Immune Cell Biology | Immune tolerance; Microbiome; Tumor infiltrating lymphocytes (TILs) |
| 513 | Poster Presentation | CD26 enzymatic activity modulates efficient migration of adoptively transferred T cells to solid tumors | Megan M. Wyatt, MS; Michelle H. Nelson, PhD; Stefanie R. Bailey, PhD; Hannah M. Knochelmann, BS; Aubrey S. Smith, BS; Guillermo O. Rangel RIvera, B.S.; Amalia M. Rivera Reyes, BS; Chrystal M. Paulos, PhD; | Immune Cell Biology | Adoptive immunotherapy; Chemokine; Costimulation; Solid tumors; T cell |
| 515 | Oral Presentation | Metabolic reprogramming of antitumor CD8+ T cell immunity | Alison Jaccard, MS; Mathias Wenes, PhD; Gábor Gyülvészi; Ping-Chih Ho, PhD; Pedro J. Romero, MD; | Immune Cell Biology | Adoptive immunotherapy; Epigenetics; Immune monitoring; Metabolism; Post-translational modifications; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 518 | Poster Presentation | Epigenetic dysfunction of terminally exhausted tumor infiltrating T cells | Rhodes Ford, BSc; Paolo DA. Vignali, BA; Natalie Rittenhouse; Nicole Scharping; Andrew Frisch; Greg M. Delgoffe, PhD; Amanda Poholek; | Immune Cell Biology | Bioinformatics; Epigenetics; Gene expression; T cell; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 521 | Poster Presentation | Immune Regulatory Metabolites in Human Ovarian Cancer | Julian J. Lum, PhD; Marisa Kilgour, BSc; Sarah MacPherson; Lauren Zacharias; Sarah Keyes; Bertrand Allard, PhD; Julian Smazynski; Peter Watson; John Stagg, PhD; Bradley Nelson, PhD; Ralph Deberardinis; Phineas Hamilton; Julian J. Lum, PhD; | Immune Cell Biology | Immune suppression; Metabolism; Tumor infiltrating lymphocytes (TILs) |
| 523 | Poster Presentation | A subset of mature neutrophils contains the strongest PMN-MDSC activity in blood and tissue of patients with head and neck cancer | Yu Si; Kirsten Bruderek; Simon Merz; Philip Jansen; Stephan Lang; Matthias Gunzer; Joachim Klode; Anthony Squire; Sven Brandau, PhD; | Immune Cell Biology | Biomarkers; Granulocyte; Immune monitoring; Inflammation; MDSC; Myeloid cells; Solid tumors; Tumor microenvironment; Tumor stroma |
| 525 | Poster Presentation | KIT mutation with a low MS4A1/CD20 expression is associated with poor prognosis in melanoma | Shashank Cingam, MD; Moises Harari-Turquie, MD; Dulcinea Quintana, MD; Leslie Andritsos, MD; Emrullah Yilmaz, MD, PhD; | Immune Cell Biology | B cell; Checkpoint blockade; Targeted therapy; Tumor microenvironment |
| 526 | Poster Presentation | InhibigenTM-specific responses suppress anti-tumor immunity and promote tumor growth | Victoria L. DeVault, PhD; Tulin Dadali, PhD; Hanna Starobinets, PhD; Kevin Lema; Stephanie Rinaldi; Osaruese Odeh; Julie N. Arnold; Dylan Sheehan; Cindy K. Nguyen; Louisa Dowal, PhD; Jessica B. Flechtner, PhD; Alberto Visintin, PhD; Hubert Lam, PhD; | Immune Cell Biology | Antigen presenting cells; Checkpoint blockade; Immune suppression; Neoantigens; T cell; Targeted therapy; Tumor antigens; Tumor microenvironment |
| 527 | Poster Presentation | Tumor organoid and immune cell co-culture system potentiates Immuno-Oncology drug development | Hongjuan Zhang, PhD; Jun Zhou; Shuang Zhu; Jia Zheng; Limei Shang; Chunmei Li; Xuefei Yan, PhD; Rui Zhang; Mingfa Zang; Annie Xiaoyu An; Xiaoxi Xu; Shuzong Wang; Henry Q. Li; Yujun Huang; | Immune Cell Biology | Bispecifics; CAR T cells; Checkpoint blockade; T cell; Tumor antigens; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
| 530 | Poster Presentation | T-cell immunoglobulin– and mucin domain–containing (TIM)–3 downregulation in response to ex vivo activation and cancer targets correlates to NK cell functionality. | Tram N. Dao, BS; Sandro Matosevic, PhD; Sagar Utturkar, PhD; Nadia A. Lanman, PhD; Sandro Matosevic, PhD; | Immune Cell Biology | Cytokine; NK/NK T cell; Solid tumors; Tumor infiltrating lymphocytes (TILs) |
| 531 | Oral Presentation | AFM13-targeted blood and cord-blood-derived memory-like NK cells as therapy for CD30+ malignancies | Lucila Kerbauy; Nancy D. Marin, PhD; Mecit Kaplan; Pinaki Banerjee; Melissa Berrien-Elliott; Michelle Becker-Hapak; Rafet Basar; Mark Foster; Luciana Garcia Melo; Carly Neal; Ethan McClain; May Daher, MD; Ana Karen Nunez Cortes; Sweta Desai; Francesca Wei Inng Lim; Mayela Carolina Mendt; Timothy Schappe; Li Li; Hila Shaim; Mayra Hernandez Sanabria; Pamela Wong; Enli Liu; Sonny Ang; Rong Cai; Vandana Nandivada; Vakul Mohanty; Yifei Shen; Natalia Baran; Natalie Fowlkes; Ken Chen; Luis Muniz-Feliciano; Joachim Koch, PhD; Martin Treder; Wolfgang Fischer; Oswaldo Keith Okamoto; Yago Nieto, MD PhD; Richard E. Champlin, MD; Elizabeth J. Shpall, MD; Todd A. Fehniger; Katy Rezvani, MD, PhD; | Immune Cell Biology | Antibody; Bispecifics; NK/NK T cell; Targeted therapy |
| 532 | Poster Presentation | SOCS3 deficiency blocked autophagy-dependent myeloid differentiation of early-stage myeloid-derived suppressor cells via the miR-155/C/EBPß/Wnt axis | Jinpu Yu, Ph.D.; Wenwen Zhang; | Immune Cell Biology | Carcinogenesis; Immune suppression; MDSC; Tumor evasion; Tumor microenvironment |
