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All odd numbered posters will be presented on Friday, November 8, 2019, while even numbered posters will be presented on Saturday, November 9, 2019.
Posters will be on display from 7 a.m. - 8 p.m., with the presenting authors required to be at their posters during lunch (12:30 - 2 p.m. on Friday, Nov. 8, and 12:35 - 2:05 p.m. on Saturday, Nov. 9) and also during the poster reception (6:30 - 8p.m. on Friday, Nov. 8, and 7 - 8:30 p.m. on Saturday, Nov. 9).
# | Title | Authors | Category | Keywords |
---|---|---|---|---|
O74 | Fibroblast activation protein is expressed by human and murine leukocytes and nonspecific inhibition of FAP enhances anti-PD-1 therapy in murine models of PDAC | Louis M. Weiner, MD; Allison Fitzgerald, MD/PhD Candidate; Shangzi Wang, PhD; | Tumor and Stromal Cell Biology | Checkpoint blockade; NK/NK T cell; Solid tumors; Tumor microenvironment; Tumor stroma |
O75 | Selective induction of S100a8/a9 heterodimer protein in pancreatic cancer in response to immune selection pressure | Louis M. Weiner, MD; Reham Ajina, MS | Tumor and Stromal Cell Biology | Immune suppression; Inflammation; Proteomics; Solid tumors; Tumor infiltrating lymphocytes (TILs); Tumor evasion; Tumor microenvironment; Tumor stroma |
O76 | Interferon-Gamma Mediated T Cell Exhaustion Generates Distinct Tumor Microenvironments in Synchronous Melanoma via PD-1/PD-L1 Axis | Peter A. Prieto, MD, MPH; Shuyang S. Qin, BS; Alyssa Williams; Booyeon Han, BS; Rachel Jewell; Katherine M. Jackson, MD; Alexander C. Chacon, MD; Edward Englerth III, BS; Brian A. Belt, JD; Goran Micevic, MD, PhD; David C. Linehan, MD; Scott Gerber, PhD; Alexandre Reuben; | Tumor and Stromal Cell Biology | Chemokine; Costimulation; Immune suppression; Immune tolerance; T cell; Tumor evasion; Tumor microenvironment; Tumor stroma |
O77 | Clinicopathological and genomic correlates of PD-L1 expression in nonsquamous non-small cell lung cancer. | Giuseppe Lamberti, MD; Liam Spurr; Yvonne Li; Biagio Ricciuti, MD; Gonzalo Recondo, MD; Renato Umeton; Andrew Cherniak; Matthew L. Meyerson, MD, PhD; Mark Awad, MD PhD; | Tumor and Stromal Cell Biology | Bioinformatics; Biomarkers; Checkpoint blockade; Solid tumors |
O78 | Identification of breast cancer neoantigens exposed by radiation therapy | Claire Lhuillier, PhD; Nils Rudqvist; Takahiro Yamazaki, PhD; Lorenzo Galluzzi; Sandra Demaria, MD; | Tumor and Stromal Cell Biology | Neoantigens; Radiotherapy; Solid tumors; Tumor antigens; Vaccine |
O79 | Mapping the spatial architecture of acute myeloid leukemia in the bone marrow microenvironment by multiplexed ion beam imaging | Xavier Rovira-Clave, PhD; Sizun Jiang, PhD; Xavier Rovira-Clave, PhD; Yunhao Bai, BS; Bokai Zhu; Marc Bosse, PhD; Michael Angelo, MD, PhD; Yara Banz, MD, PhD; Christian M. Schürch, MD, PhD; Garry P. Nolan, PhD; | Tumor and Stromal Cell Biology | B cell; Checkpoint blockade; Immune monitoring; Leukemia/Lymphoma; Myeloid cells; Proteomics; T cell; Tumor evasion; Tumor microenvironment; Tumor stroma |
O80 | Atlas of clinically-distinct cell states and cellular ecosystems across human solid tumors | Bogdan Luca; Ash Alizadeh; Max Diehn; Aaron Newman; Andrew Gentles, PhD; Chloé Steen; Andrew Gentles, PhD; | Tumor and Stromal Cell Biology | Bioinformatics; Biomarkers; Gene expression; Immune contexture; Systems biology; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment; Tumor stroma |
P834 | The actin regulatory protein hMENA is a key player in the paracrine TGF-β mediated crosstalk between tumor cells and cancer associated fibroblasts | Paola Nistico', MD; Roberta Melchionna; Paola Trono; Francesca Di Modugno, PhD; Anna Di Carlo; Sheila Spada, PhD; Giuliana Falasca; Isabella Sperduti; Barbara Antoniani; Daniel D'Andrea; Paolo Visca; Gian Luca Grazi; Francesco Facciolo; Aldo Scarpa; Paola Nistico', MD; | Tumor and Stromal Cell Biology | Solid tumors; Tumor microenvironment; Tumor stroma |
P835 | The role of sialylation in stromal cell mediated immunosuppression in the colorectal tumour microenvironment | Aideen E. Ryan, PhD; Hannah Egan, BSC; Kevin Lynch, PhD; Niamh Leonard, MSc; Michael O; Laurence J. Egan, MD; Thomas Ritter; Oliver Treacy, PhD; Aideen E. Ryan, PhD; | Tumor and Stromal Cell Biology | Immune suppression; Inflammation; Monocyte/Macrophage; Solid tumors; T cell; Tumor stroma |
P836 | Immunopathological properties of the fibroblastic niche for cancer stem cells and the niche-targeted immunotherapy | Toshihiko Torigoe, MD, PhD; Yoshihiko Hirohashi, MD, PhD; Toshihiko Torigoe, MD, PhD; | Tumor and Stromal Cell Biology | Stem cell/cancer-initiating cell; Solid tumors; Tumor antigens; Tumor microenvironment; Tumor stroma |
P837 | Roles of nitric oxide synthase and cyclooxygenase inhibition in potentiating immune response in murine models of 4T1 mammary tumor | Veena Somasundaram, PhD; Anne C. Gilmore; Debashree Basudhar; Erika Palmieri; David A. Scheiblin; William F. Heinz; Robert Cheng; Lisa Ridnour, PhD; Stephen J. Lockett; Daniel W. McVicar, PhD; David A. Wink; | Tumor and Stromal Cell Biology | Biomarkers; Inflammation; Myeloid cells; Tumor microenvironment |
P838 | Disrupting hypoxic tumor niches to sensitize pancreatic cancer to immunotherapy | Arthur J. Liu, BS; Michael A. Curran, PhD; | Tumor and Stromal Cell Biology | Angiogenesis; Immune suppression; Solid tumors; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
P839 | DNA demethylating agent sensitizes lung cancer cells to immune attack of γδ T cells | Rueyhung R. Weng, PhD; Chien-Ting Lin; Hsuan-Hsuan Lu; Chong-Jen Yu; Hsing-Chen Tsai; | Tumor and Stromal Cell Biology | Chemotherapy; Proteomics; Solid tumors; T cell; Tumor antigens |
P840 | Characterization of syngeneic tumor models and their microenvironment for immunotherapeutic approaches | Marco Carretta, PhD; Marie Louise Thorseth; Dennis A. Agardy; Silvia Redondo Garcia; Anne Mette Hvid Larsen, M.Sc; Dorota E. Kuczek, MSc; Daniel H. Madsen; | Tumor and Stromal Cell Biology | Solid tumors; Tumor microenvironment |
P841 | NCG/CRL as a novel (Charles River) humanized mouse model for pre-clinical oncology studies: immunophenotypic characterization and performance monitoring | Jenny Rowe, PhD; Christoph CE. Eberle, PhD; Jenny Rowe, PhD; Robert Mihalek, PhD; Stephen Festin; | Tumor and Stromal Cell Biology | Checkpoint blockade; Immune monitoring; Leukemia/Lymphoma; Myeloid cells; NK/NK T cell; Solid tumors; T cell; T cell lineages; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
P843 | Oral cancers expressing Glycoprotein-A repetitions predominant (GARP) show poor prognosis | Rieneke van de Ven, PhD; Jan Kloosterman, Bsc; Irene H. Nauta, M.Sc; Sonja H. Ganzevles, BSc; Elisabeth Bloemena, Prof. Dr.; C. René Leemans, MD, PhD; Ruud H. Brakenhoff, MD, PhD; | Tumor and Stromal Cell Biology | Biomarkers; Immune suppression; Immune tolerance; Solid tumors; Tumor evasion; Tumor microenvironment |
P844 | Investigating the immunologic landscape and tumor-specific target identification in human clear cell renal carcinoma | Nivedita Chowdhury, MS; Aleksandar Obradovic; David H. Aggen, MD, PhD; Michael Johnson; Charles G. Drake, MD, PhD; | Tumor and Stromal Cell Biology | Neoantigens; Solid tumors; T cell; Tumor infiltrating lymphocytes (TILs); Tumor antigens; Tumor microenvironment |
P845 | Targeting of Lactate Dehydrogenase C and its effects on the tumor immune microenvironment: two birds with one stone | Adviti Naik, PhD; Julie Decock, PhD; Aljazi M. Al-Khalifa; | Tumor and Stromal Cell Biology | Carcinogenesis; Cytokine; Gene expression; Immune contexture; Immune suppression; Metabolism; Solid tumors; Tumor antigens; Tumor evasion; Tumor microenvironment |
P846 | Tumor-infiltrating B cells control the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8+ T cells | Kamila Hladíková; Vladimír Koucký; Jan Boucek; Jan Laco; Marek Grega; Aleš Ryška; Radek Špíšek; Anna Fialová; | Tumor and Stromal Cell Biology | B cell; Carcinogenesis; Checkpoint blockade; Costimulation; T cell; Tumor infiltrating lymphocytes (TILs); Tumor microenvironment |
P847 | Macrophages-induced H19 Up-regulation Activate the miR-193b/MAPK1 Axis and Promotes Cell Aggressiveness in Hepatocellular Carcinoma | Yingnan Ye; Jinpu Yu; Yingnan Ye; | Tumor and Stromal Cell Biology | Biomarkers; Monocyte/Macrophage; Tumor microenvironment |
P848 | MiR-17 Cluster Promoted M2-polarized Tumor Associated Macrophages Related Cell Aggressiveness via Inducing the Imbalance of TGF-β1 /BMP7 Pathways in Hepatocellular Carcinoma | Yingnan Ye; Junya Ning; Jinpu Yu; | Tumor and Stromal Cell Biology | Monocyte/Macrophage; Tumor microenvironment |