BRECIS Program Schedule

Monday April 13, 2015
Session 1: Epidemiology and Biology
Moderators: Naser Elkum and Abdelilah Aboussekhra
07.00 – 08.00 Registration and refreshments
08.00 – 08.05 Welcome note
Davide Bedognetti
Director Tumor Biology, Immunology, and Therapy Section, Sidra Medical and Research Center, Qatar
08.05 – 08.25 Breast cancer control in Qatar
Salha Boujassoum Al Badar
Senior Consultant Hematology/Oncology, National Center for Cancer and Research, Hamad Medical Corporation, Qatar
08.25 – 08.30 Questions and answers
08.30 – 08.50 Triple negative and inflammatory breast cancer in Arab countries: A clue for personalized therapy
Hammouda Boussen
Professor, Department of Medical Oncology, A Mami Hospital, Tunisi
08.50 – 08.55 Questions and answers
08.55 – 09.15 Breast cancer in Arab Populations: The search for genes associated with aggressive form
Lotfi Chouchane
Professor of Genetic Medicine, Weill Cornell Medical College- Qatar, Qatar
09.15 – 09.20 Questions and answers
09.20 – 09.40 Mechanisms of tumor microenvironmental hypoxia-induced immune resistance
Salem Chouaib
Director, Integrated Research Cancer Institute, Gustave Roussy, France
09.40 – 09.45 Questions and answers
09.45 – 10.00 QNRF funding in medical research  PDF
Thenaa Said
Program Manager, Biomedical and Health Sciences, Qatar National Research Fund, Qatar
10.00 – 10.05 Questions and answers
10.05 – 10.25 Comfort Break
10.25 – 10.45 Alterations of the tumor microenvironment by HER-2-neu-induced CREB activation and localization and hypoxia in mammary carcinoma: CREB as a novel therapeutic target for this disease?
Barbara Seliger
Professor, Martin Luther University Halle-Wittenberg, Germany
10.45 – 10.50 Questions and answers
10.50 – 11.10

 
Expression profiling of inflammatory breast cancer  PDF
Francois Bertucci
Professor, Institut Paoli-Calmettes, Université de la Méditerranée, France
11.10 – 11.15 Questions and answers
11.15 – 11.35 Identification of novel master regulators of inflammatory breast cancer by system biology approaches
Michele Ceccarelli
Senior Scientist, Qatar Computing Research Institute, Qatar
11.35 – 11.40 Questions and answers
11.40 – 12.00 Dendritic cells and breast cancer  PDF
Karolina Palucka
Professor and associate director of cancer immunology, The Jackson Laboratory, USA
12.00 – 12.05 Questions and answers
12.05 – 13.10 Lunch and poster viewing
Oral Abstract session 1
Moderator: Emmanuel Akporiaye
13.10 – 13.22 Foxp3 expression in breast cancer patient from Qatar: Survival analysis  PDF
Mahmoud Mohamed
Weill Cornell Medical College-Qatar, Qatar
13.22 – 13.25 Questions and answers
13.25 – 13.37 Clinico-pathological and transcriptomic determinants of SLFN11 expression in invasive breast carcinoma  PDF
Gabriele Zoppoli
Department of Internal Medicine (DiMI), University of Genova, Italy
13.37 – 13.40 Questions and answers
13.40 – 13.52 The sialyl-glycolipid SSEA4 marks a subpopulation of chemotherapy resistant breast cancer cells with mesenchymal features  PDF
Andrea Aloia
Institute for Molecular Health Sciences, ETH Zurich, Switzerland /Miltenyi Biotec GmbH, Germany
13.52 – 13.55 Questions and answers
13.55 – 14.05 Comfort Break
Session 2: Biomarkers
Moderators: Mohammed Haris and Sandra Demaria
14.05 – 14.25 Prognostic and predictive role of tumour-infiltrating lymphocytes in breast cancer  PDF
Carsten Denkert
Head, Translational Cancer Research Group at the Institute of Pathology, Charite University, Germany
14.25 – 14.30 Questions and answers
14.30 – 14.50 The Qatari breast cancer immunoscore project: A road map of what we know
Shahinaz Bedri
Assistant Professor of Pathology and Laboratory Medicine, Weill Cornell Medical College-Qatar, Qatar
14.50 – 14.55 Questions and answers
14.55 – 15.15 Serologic identification of tumor antigen in breast cancer
Sam Hanash
Director, Red and Charline McCombs Institute for the Early Detection and Treatment of Cancer, University of Texas MD Anderson Cancer Center, USA
15.15 – 15.20 Questions and answers
15.20 – 15.45 Biomarkers of response to cancer immunotherapy
Davide Bedognetti
Director Tumor Biology, Immunology, and Therapy Section, Sidra Medical and Research Center, Qatar
15.45 – 15.50 Questions and answers
15.50 – 16.10 Breast cancer immune-subtypes and prognostic implications  PDF
Lance Miller
Core Director, Comprehensive Cancer Center, Wake Forest School of Medicine, USA
16.10 – 16.15 Questions and answers

 

Tuesday  April 14, 2015
Session 3: Therapeutics (clinical and preclinical studies)
Moderators: Alexander Knuth and Mario Roberto Sertoli
07.00 – 08.00 Registration and refreshments
08.00 – 08.05 Welcome note and keynote speaker introduction
Emmanuel Akporiaye
Division Chief Experimental Biology, Sidra Medical and Research Center, Qatar
08.05 – 08.35 KEYNOTE LECTURE: Cancer Immunotherapy Trials Network: High-priority immunotherapy agents in development
Martin Cheever
Director, Cancer Immunotherapy Trials Network, Member, Fred Hutchinson Cancer Research Center, USA
08.35 – 08.55 Generating immunity to breast cancer  PDF
Nora Disis
Professor, Department of Medicine, University of Washington, USA
08.55 – 09.00 Questions and answers
09.00 – 09.20 The PD-1 pathway: A therapeutic target in breast cancer  PDF
Leisha Emens
Associate Professor of Oncology, John Hopkins Medicine, USA
09.20 – 09.25 Questions and answers
09.25 – 09.45 Clinical development of HER2-derived peptide vaccines  PDF
Elizabeth Mittendorf
Associate Professor, Department of Surgical OncologyThe University of Texas MD Anderson Cancer Center, USA
09.45 – 09.50 Questions and answers
09.50 – 10.10 Immuno-Oncology clinical studies: The model of breast cancer  PDF
Giuseppe Curigliano
Co-Chair of the Division of Medical Oncology, European Institute of Oncology, Italy
10.10 – 10.15 Questions and answers
10.15 – 10.35 Comfort Break
10.35 – 10.55 Innate immunotherapy to enhance the efficacy of tumor targeting antibodies including trastruzumab for HER2+ breast cancer  PDF
Holbrook Kohrt
Assistant Professor, Stanford School of Medicine, USA
10.55 – 11.00 Questions and answers
11.00 – 11.20 Adoptive T-cell transfer in breast cancer patients - experiences from a phase 1/2 trial  PDF
Florian Schuetz
Deputy Director, Women´s Hospital, Heidelberg University, Germany
11.20 – 11.25 Questions and answers
Oral Abstract session 2
Moderator: Emmanuel Akporiaye
11.25 – 11.37 CTLA-4 checkpoint blockade in breast cancer: A case in point report  PDF
Chiara Dellepiane
IRCCS San Martino Institute, Genoa University, Italy
11.37 – 11.40 Questions and answers
11.40 – 11.52 Pre-operative immunotherapy with tumor cryoablation (cryo) plus ipilimumab (ipi) induces potentially favorable systemic and intratumoral immune effects in early stage breast cancer (ESBC) patients  PDF
David Page
Memorial Sloan Kettering Cancer Center, USA
11.52 – 12.00 Questions and answers
12.00 – 12.12 Long-term in vivo expression of trastuzumab following intramuscular electrotransfer of the encoding DNA in mice
Kevin Hollevoet
Laboratory for Therapeutic and Diagnostic Antibodies, Leuven University, Belgium
12.12 – 12.15 Questions and answers
12.15 – 12.27 Immune profiling in human breast cancers using high-sensitivity detection and analysis predicts outcome: longitudinal studies
Brendon Coventry
University of Adelaide, Australia
12.27 – 12.30 Questions and answers
12.30 – 12.35 Travel Award Ceremony
12.35 – 13.35 Lunch and poster rviewing
13.35 – 13.55 In situ vaccination by radiation in breast cancer
Sandra Demaria
Professor of Pathology and Radiation Oncology, New York University, USA
13.55 – 14.00 Questions and answers
14.00 – 14.20 Alpha-TEA, a novel cancer therapeutic: Journey from the bench to the clinic
Emmanuel Akporiaye
Division Chief Experimental Biology, Sidra Medical and Research Center, Qatar
14.20 – 14.25 Questions and answers
14.25 – 14.35 Closing remarks
Emmanuel Akporiaye
Division Chief Experimental Biology, Sidra Medical and Research Center, Qatar

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