SITC 2018 Abstracts

Impact of Diet, Exercise, and/or Stress on Antitumor Immunity

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#TitleAuthorsKeywords
P504Nutritional measures to boost immunosurveillance of breast cancer by NK cellsLorenzo Galluzzi, PhD; Aitziber Buqué, PhD; Maria Perez-Lanzon, M.Sc (Master of Science); Guido Kroemer, MD, PhD; Takahiro Yamazaki, PhD;Checkpoint blockade; Gene expression; Immune suppression; Metabolism; NK/NK T cell; Solid tumors; Tumor evasion
P505The gut microbiome of metastatic melanoma patients initiating systemic therapy is influenced by host factors including diet, probiotic and antibiotic useVancheswaran Gopalakrishnan, MPH, PhD; Christine N. Spencer, PhD; Jennifer L. McQuade, MD; Miles Andrews, MD, PhD; Beth Helmink, MD PhD; Alexandria P. Cogdill, MEng; Md AW. Khan; Elizabeth Sirmans; Lauren E. Haydu, MS, BChe, MIPH; Eliza Posada; Elizabeth Burton; Isabella C. Glitza, MD, PhD; Rodabe N. Amaria, MD; Sapna Patel, MD; Adi Diab, MD; Michael K. Wong, MD PhD FRCPC; Hussein A. Tawbi, MD, PhD; Wen-Jen Hwu, MD, PhD; Michael Davies, MD, PhD; Patrick Hwu, MD; Robert Jenq, MD; Kelly Nelson, MD; Carrie Daniel-MacDougall, MPH, PhD; Lorenzo Cohen; Jennifer A. Wargo, MD, MMSc; Checkpoint blockade; Epidemiology; Microbiome
P506Subcutaneous and intramuscular fat indices predict survival in advanced stage cancer patients treated with immunotherapyDylan J. Martini, BA; Julie M. Shabto, BA; Yuan Liu, PhD; Milton Williams; Amir I. Khan; Colleen Lewis; Hannah Collins; Mehmet Akce; Haydn T. Kissick; Bradley C. Carthon, MD, PhD; Walid L. Shaib, MD; Olatunji B. Alese, MD; Conor Steuer, MD; Christina Wu, MD; David H. Lawson, MD; Ragini R. Kudchadkar, MD; Bassel El-rayes, MD; Suresh S. Ramalingam, MD; Taofeek K. Owonikoko, MD, PhD; R. Donald Harvey, PharmD; Viraj A. Master, MD, PhD; Mehmet A. Bilen, MD; Biomarkers; Checkpoint blockade; Metabolism; Solid tumors; Tumor microenvironment
P507Body mass index as a predictor of survival in advanced stage cancer patients treated with immunotherapyJulie M. Shabto, BA; Dylan J. Martini, BA; Yuan Liu, PhD; Milton Williams; Amir I. Khan; Colleen Lewis; Hannah Collins; Mehmet Akce; Haydn T. Kissick; Bradley C. Carthon, MD, PhD; Walid L. Shaib, MD; Olatunji B. Alese, MD; Conor Steuer, MD; Christina Wu, MD; David H. Lawson, MD; Ragini R. Kudchadkar, MD; Bassel El-rayes, MD; Suresh S. Ramalingam, MD; Viraj A. Master, MD, PhD; Taofeek K. Owonikoko, MD, PhD; R. Donald Harvey, PharmD; Mehmet A. Bilen, MDBiomarkers; Checkpoint blockade; Clinical trial; Metabolism; Solid tumors; Tumor microenvironment
P508Obesity promotes PD-1 mediated T cell dysfunction and tumor pro-gression but superior anti-tumor effects upon checkpoint blockadeZiming Wang, MS; Jesus I. Luna, Ph.D.; Cordelia Dunai, MS; Lam T. Khuat; Catherine T. Le, BS; Ethan G. Aguilar; Annie Mirsoian; Christine M. Minnar, PhD; Kevin M. Stoffel, MS; Ian Sturgill; Steven Grossenbacher; Robert Canter, MD, MAS, FACS; Arta Monjazeb, MD, PhD; William J. Murphy, PhD; Ziming Wang, MSCheckpoint blockade; Metabolism